I good with them sticking out of the fenders some, Im worried about the wheel bearings.Depends what you are looking for with the wheel. Do you want them to stick out a bit beyond the fender? Be flush with the fender? etc etc
Also, the question of the spokes clearing the calipers comes up.
A 17x8 with 4.5" of backspacing will stick out a little bit past the fenders.