As one that won't argue using top tier fuel is the best idea to begin with, it's still not a bad idea to use a fuel additive to help keep the fuel system clean every once in a while.
For me I personally like to use Berryman's B-12 Chemtool every 5,000 miles(aka every oil change service). Does it make the vehicle gain a lot of power or somehow fix a problem? Not necessarily, but it does help keep the fuel system clean.
That said because you do have a direct injected engine on your truck it is highly recommended to do an induction service every 30,000 to 40,000 mi. This will help keep the intake valves clean over time. If you don't have the tools to performs head service you are more than welcome to talk to a local dealership or shop that you trust to get an idea of what that service involves.
